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Setting up the characteristics of default fonts is a matter of setting various Mozilla Preferences. Since the topic comes up regularly, we will give it its own space for some special attention here.
All of the font preferences work on a per-encoding basis, meaning that to set any particular characteristic, you may have to set multiple prefs for all of the different encodings that you use.
1. Minimum Size
session_pref("font.minimum-size.x-western", 32);
2. Default Fonts
session_pref("font.name.serif.x-western", "Gentium");